MOTS-c – Research Peptide for Mitochondrial Function, Metabolic Health, and Cellular Resilience
Product Usage: All products made available on this website are intended exclusively for research and development purposes and are strictly not for human consumption or therapeutic use. These products are not approved by the U.S. Food and Drug Administration (FDA), and no statements on this website have been evaluated by the FDA. The products and any information provided are not intended to diagnose, treat, cure, or prevent any disease or medical condition.
MOTS-c is a mitochondrial-derived peptide (MDP) studied for its role in regulating metabolism, enhancing cellular stress responses, and promoting healthy aging. Unlike traditional nuclear-encoded peptides, MOTS-c is encoded by mitochondrial DNA and functions as a signaling molecule that helps maintain metabolic balance under stress. Research suggests its potential in improving insulin sensitivity, fat utilization, and resilience against age-related decline.
Potential Research Benefits:
- Mitochondrial Optimization: MOTS-c supports mitochondrial homeostasis and energy regulation, particularly under metabolic or oxidative stress.
- Glucose and Lipid Metabolism: Preclinical studies indicate improvements in insulin sensitivity and fatty acid oxidation, making it relevant to obesity and type 2 diabetes models.
- Exercise and Physical Performance: Animal models show enhanced endurance, muscle adaptation, and fatigue resistance, suggesting performance-enhancing effects.
- Cellular Stress Resilience: Plays a role in activating AMPK and other protective pathways, improving cellular responses to metabolic dysfunction.
- Healthy Aging and Longevity Support: MOTS-c has shown potential in extending healthspan by reducing inflammation, oxidative stress, and metabolic decline in aging models.
Clinical Research References:
- MOTS-c is being explored in both in vitro and in vivo studies for its unique role in mitochondrial signaling, age-related metabolic disorders, and performance adaptation.
Storage and Handling:
- Store at 2–8°C (35–46°F) in a refrigerated environment.
- Protect from moisture, light, and extreme temperatures.
- If reconstituted with bacteriostatic water, refrigerate and use within 4–6 weeks for best results.
Disclaimer:
This product is intended strictly for research purposes only. Not for human consumption or therapeutic use. Researchers are responsible for ensuring compliance with applicable laws and regulations.


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